Breaking the Wall of Paraplegia How Neuroscience Can Help Spine- and Brain-Injured Patients
(eVideo)
Published
New York, N.Y. : Infobase, [2012], c2009.
Status
Description
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Subjects
Other Subjects
More Details
Format
eVideo
Language
English
Notes
General Note
Encoded with permission for digital streaming by Infobase on September 03, 2012.
General Note
Classroom Video On Demand is distributed by Infobase for Films for the Humanities & Sciences, Cambridge Educational, Meridian Education, and Shopware.
General Note
Part of the series Falling Walls Conference.
Restrictions on Access
Access requires authentication through Classroom Video On Demand.
Creation/Production Credits
Features Martin E. Schwab.
Description
In the brain and spinal cord, regrowth of injured nerve fibers happens only to a very limited extent. Previously this meant recovery after injury was impossible - but new experimental therapy has allowed regeneration of injured nerve fibers in rats with broken backs, leading to significant recovery of function. In this video from the 2009 Falling Walls Conference, Martin E. Schwab lectures on his discovery that the spinal cord and brain contain the protein Nogo-A, which has a strong inhibitory effect on the growth of nerve fibers. Schwab first purified Nogo-A and then produced function-blocking antibodies which defeat this growth-inhibiting signal. The functions that the rats, mice, and monkeys had lost after spinal cord or brain injuries, such as locomotion, swimming, climbing, and fine hand-reaching movements all returned, indicating that these antibodies could help reduce severe disability in human patients.
Target Audience
10 & up.
System Details
Mode of access: Internet.
System Details
System requirements: Classroom Video On Demand playback platform.
Language
Closed-captioned.
Citations
APA Citation, 7th Edition (style guide)
(20122009). Breaking the Wall of Paraplegia: How Neuroscience Can Help Spine- and Brain-Injured Patients . Infobase.
Chicago / Turabian - Author Date Citation, 17th Edition (style guide)20122009. Breaking the Wall of Paraplegia: How Neuroscience Can Help Spine- and Brain-Injured Patients. Infobase.
Chicago / Turabian - Humanities (Notes and Bibliography) Citation, 17th Edition (style guide)Breaking the Wall of Paraplegia: How Neuroscience Can Help Spine- and Brain-Injured Patients Infobase, 20122009.
MLA Citation, 9th Edition (style guide)Breaking the Wall of Paraplegia: How Neuroscience Can Help Spine- and Brain-Injured Patients Infobase, 20122009.
Note! Citations contain only title, author, edition, publisher, and year published. Citations should be used as a guideline and should be double checked for accuracy. Citation formats are based on standards as of August 2021.
Staff View
Grouped Work ID
4eb1fab5-f356-8ca0-b735-431a6b8fb7c4-eng
Grouping Information
| Grouped Work ID | 4eb1fab5-f356-8ca0-b735-431a6b8fb7c4-eng |
|---|---|
| Full title | breaking the wall of paraplegia how neuroscience can help spine and brain injured patients |
| Author | falling walls foundation |
| Grouping Category | movie |
| Last Update | 2023-01-17 14:42:32PM |
| Last Indexed | 2024-06-25 23:31:47PM |
Book Cover Information
| Image Source | classroomVideoOnDemand |
|---|---|
| First Loaded | Aug 3, 2023 |
| Last Used | Dec 18, 2023 |
Marc Record
| First Detected | Mar 05, 2013 12:00:00 AM |
|---|---|
| Last File Modification Time | Jan 17, 2023 02:48:17 PM |
MARC Record
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| 245 | 0 | 0 | |a Breaking the Wall of Paraplegia|h [electronic resource (video)] :|b How Neuroscience Can Help Spine- and Brain-Injured Patients /|c Falling Walls Foundation. |
| 246 | 3 | |a How Neuroscience Can Help Spine- and Brain-Injured Patients | |
| 260 | 3 | |a New York, N.Y. :|b Infobase,|c [2012], c2009. | |
| 300 | |a 1 streaming video file (16 min.) :|b sd., col. | ||
| 500 | |a Encoded with permission for digital streaming by Infobase on September 03, 2012. | ||
| 500 | |a Classroom Video On Demand is distributed by Infobase for Films for the Humanities & Sciences, Cambridge Educational, Meridian Education, and Shopware. | ||
| 500 | |a Part of the series Falling Walls Conference. | ||
| 505 | 0 | |a Introduction to the Central Nervous System (2:26) -- Devastating Spinal Cord Injuries (1:01) -- A Breakthrough Paraplegia Discovery (3:44) -- Discovering a Nerve Cell Growth Inhibitor (0:50) -- Testing Paraplegia Therapy on Lab Animals (3:11) -- Recovery of Nerve Function (3:00) -- Medical Breakthrough in Brain Injuries (1:52) | |
| 506 | |a Access requires authentication through Classroom Video On Demand. | ||
| 508 | |a Features Martin E. Schwab. | ||
| 520 | |a In the brain and spinal cord, regrowth of injured nerve fibers happens only to a very limited extent. Previously this meant recovery after injury was impossible - but new experimental therapy has allowed regeneration of injured nerve fibers in rats with broken backs, leading to significant recovery of function. In this video from the 2009 Falling Walls Conference, Martin E. Schwab lectures on his discovery that the spinal cord and brain contain the protein Nogo-A, which has a strong inhibitory effect on the growth of nerve fibers. Schwab first purified Nogo-A and then produced function-blocking antibodies which defeat this growth-inhibiting signal. The functions that the rats, mice, and monkeys had lost after spinal cord or brain injuries, such as locomotion, swimming, climbing, and fine hand-reaching movements all returned, indicating that these antibodies could help reduce severe disability in human patients. | ||
| 521 | 2 | |a 10 & up. | |
| 538 | |a Mode of access: Internet. | ||
| 538 | |a System requirements: Classroom Video On Demand playback platform. | ||
| 546 | |a Closed-captioned. | ||
| 588 | |a Title from distributor's description. | ||
| 650 | 0 | |a Brain|x Physiology. | |
| 650 | 0 | |a Paraplegia. | |
| 655 | 0 | |a Educational films. | |
| 655 | 0 | |a Internet videos. | |
| 655 | 7 | |a Videorecording.|2 local | |
| 710 | 2 | |a Falling Walls Foundation. | |
| 710 | 2 | |a Films for the Humanities & Sciences (Firm) | |
| 710 | 2 | |a Infobase. | |
| 856 | 4 | 0 | |z Part of the Classroom Video On Demand collection.|u https://cvod.infobase.com/PortalPlaylists.aspx?xtid=49421&wID=277820 |
| 856 | 4 | 2 | |z Cover image|u https://cdnsecakmi.kaltura.com/p/1067292/sp/106729200/thumbnail/entry_id/0_6fau6pk6/version/100001/width/88 |